Oxidative damage and chemokine production dominate days before immune cell infiltration and EAE disease debut

BACKGROUND: Multiple sclerosis is widely accepted as an inflammatory disease. However, studies indicate that degenerative processes in the CNS occur prior to inflammation. In the widely used animal model experimental autoimmune encephalomyelitis (EAE), we investigated the significance of degenerativ...

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Bibliografske podrobnosti
izdano v:J Neuroinflammation
Main Authors: Hasseldam, Henrik, Rasmussen, Rune Skovgaard, Johansen, Flemming Fryd
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5024447/
https://ncbi.nlm.nih.gov/pubmed/27630002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0707-3
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