High-Fidelity Reprogrammed Human IPSCs Have a High Efficacy of DNA Repair and Resemble hESCs in Their MYC Transcriptional Signature

Human induced pluripotent stem cells (hiPSCs) are reprogrammed from adult or progenitor somatic cells and must make substantial adaptations to ensure genomic stability in order to become “embryonic stem cell- (ESC-) like.” The DNA damage response (DDR) is critical for maintenance of such genomic int...

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Detaylı Bibliyografya
Yayımlandı:Stem Cells Int
Asıl Yazarlar: Nagaria, Pratik K., Robert, Carine, Park, Tea Soon, Huo, Jeffrey S., Zambidis, Elias T., Rassool, Feyruz V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Hindawi Publishing Corporation 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5023833/
https://ncbi.nlm.nih.gov/pubmed/27688775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/3826249
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