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p62-enriched inclusion bodies in macrophages protect against atherosclerosis
Autophagy is a catabolic cellular mechanism that degrades dysfunctional proteins and organelles. Atherosclerotic plaque formation is enhanced in mice with macrophages that cannot undergo autophagy because of a deficiency of an autophagy component such as ATG5. We showed that exposure of macrophages...
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| Gepubliceerd in: | Sci Signal |
|---|---|
| Hoofdauteurs: | , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5023144/ https://ncbi.nlm.nih.gov/pubmed/26732762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aad5614 |
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