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The role of autonomic efferents and uncoupling protein 1 in the glucose-lowering effect of leptin therapy
OBJECTIVE: Leptin reverses hyperglycemia in rodent models of type 1 diabetes (T1D). Direct application of leptin to the brain can lower blood glucose in diabetic rodents, and can activate autonomic efferents and non-shivering thermogenesis in brown adipose tissue (BAT). We investigated whether lepti...
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| Publicado no: | Mol Metab |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5021671/ https://ncbi.nlm.nih.gov/pubmed/27656409 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.06.009 |
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