Leptin Administration Enhances Islet Transplant Performance in Diabetic Mice

Islet transplantation is an effective method to obtain long-term glycemic control for patients with type 1 diabetes, yet its widespread use is limited by an inadequate supply of donor islets. The hormone leptin has profound glucose-lowering and insulin-sensitizing action in type 1 diabetic rodent mo...

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Hauptverfasser: Denroche, Heather C., Quong, Whitney L., Bruin, Jennifer E., Tudurí, Eva, Asadi, Ali, Glavas, Maria M., Fox, Jessica K., Kieffer, Timothy J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Diabetes Association 2013
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717838/
https://ncbi.nlm.nih.gov/pubmed/23656888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-1684
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