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Sulforaphane Induces Neurovascular Protection Against a Systemic Inflammatory Challenge via Both Nrf2-Dependent and Independent Pathways

Sepsis is often characterized by an acute brain inflammation and dysfunction, which is associated with increased morbidity and mortality worldwide. Preventing cerebral leukocyte recruitment may provide the key to halt progression of systemic inflammation to the brain. Here we investigated the influe...

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Detalhes bibliográficos
Publicado no:Vascul Pharmacol
Main Authors: Holloway, Paul M., Gillespie, Scarlett, Becker, Felix, Vital, Shantel A., Nguyen, Victoria, Alexander, J. Steven, Evans, Paul C., Gavins, Felicity N. E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021608/
https://ncbi.nlm.nih.gov/pubmed/27401964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vph.2016.07.004
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