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The isothiocyanate sulforaphane modulates platelet function and protects against cerebral thrombotic dysfunction

BACKGROUND AND PURPOSE: Platelet activation provides a critical link between inflammation and thrombosis. Sulforaphane (SFN), a naturally occurring isothiocyanate, has been shown to display both anti‐inflammatory and anti‐thrombotic actions in the systemic microvasculature. As inflammation promotes...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Gillespie, Scarlett, Holloway, Paul M, Becker, Felix, Rauzi, Francesca, Vital, Shantel A, Taylor, Kirk A, Stokes, Karen Y, Emerson, Michael, Gavins, Felicity N E
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6057901/
https://ncbi.nlm.nih.gov/pubmed/29797311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14368
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