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Fpr2/ALX Regulates Neutrophil-Platelet Aggregation and Attenuates Cerebral Inflammation: Impact for Therapy in Cardiovascular Disease

BACKGROUND: Platelet activation at sites of vascular injury is essential for hemostasis, but it is also a major pathomechanism underlying ischemic injury. As anti-inflammatory therapies limit thrombosis and anti-thrombotic therapies reduce vascular inflammation, we tested the therapeutic potential o...

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Publicado en:Circulation
Main Authors: Vital, Shantel A., Becker, Felix, Holloway, Paul M., Russell, Janice, Perretti, Mauro, Granger, D. Neil, Gavins, Felicity N. E.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889496/
https://ncbi.nlm.nih.gov/pubmed/27154726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.115.020633
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