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Sulforaphane inhibits multiple inflammasomes through an Nrf2-independent mechanism

The inflammasomes are intracellular complexes that have an important role in cytosolic innate immune sensing and pathogen defense. Inflammasome sensors detect a diversity of intracellular microbial ligands and endogenous danger signals and activate caspase-1, thus initiating maturation and release o...

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Bibliografske podrobnosti
izdano v:J Leukoc Biol
Main Authors: Greaney, Allison J., Maier, Nolan K., Leppla, Stephen H., Moayeri, Mahtab
Format: Artigo
Jezik:Inglês
Izdano: Society for Leukocyte Biology 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673482/
https://ncbi.nlm.nih.gov/pubmed/26269198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3A0415-155RR
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