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Arsenic trioxidesand other arsenical compounds inhibit the NLRP1, NLRP3, and NAIP5/NLRC4 inflammasomes
Inflammasomes are large cytoplasmic multi-protein complexes that activate caspase-1 in response to diverse intracellular danger signals. Inflammasome components termed NOD-like receptor proteins (NLRs) act as sensors for pathogen associated molecular patterns, stress or danger stimuli. We discovered...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3884817/ https://ncbi.nlm.nih.gov/pubmed/24337744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301434 |
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