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Effect of biophysical properties of Phosphatidylserine (PS) particle on immune tolerance induction towards Factor VIII in a Hemophilia A mouse model
A major complication in the replacement therapy of Factor FVIII (FVIII) for Hemophilia A (HA) is the development of unwanted immune responses. Previous studies from our lab have shown that pretreatment of FVIII in the presence of Phosphatidylserine (PS) resulted in hyporesponsiveness to subsequent a...
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| Vydáno v: | J Pharm Sci |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5021571/ https://ncbi.nlm.nih.gov/pubmed/27431011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2016.06.008 |
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