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Detecting Cooperativity between Transcription Factors Based on Functional Coherence and Similarity of Their Target Gene Sets

In eukaryotic cells, transcriptional regulation of gene expression is usually achieved by cooperative transcription factors (TFs). Therefore, knowing cooperative TFs is the first step toward uncovering the molecular mechanisms of gene expression regulation. Many algorithms based on different rationa...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Wu, Wei-Sheng, Lai, Fu-Jou
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021274/
https://ncbi.nlm.nih.gov/pubmed/27623007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162931
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