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Properly defining the targets of a transcription factor significantly improves the computational identification of cooperative transcription factor pairs in yeast

BACKGROUND: Transcriptional regulation of gene expression in eukaryotes is usually accomplished by cooperative transcription factors (TFs). Computational identification of cooperative TF pairs has become a hot research topic and many algorithms have been proposed in the literature. A typical algorit...

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Pubblicato in:BMC Genomics
Autori principali: Wu, Wei-Sheng, Lai, Fu-Jou
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682405/
https://ncbi.nlm.nih.gov/pubmed/26679776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-16-S12-S10
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