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Detecting Cooperativity between Transcription Factors Based on Functional Coherence and Similarity of Their Target Gene Sets

In eukaryotic cells, transcriptional regulation of gene expression is usually achieved by cooperative transcription factors (TFs). Therefore, knowing cooperative TFs is the first step toward uncovering the molecular mechanisms of gene expression regulation. Many algorithms based on different rationa...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Wu, Wei-Sheng, Lai, Fu-Jou
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021274/
https://ncbi.nlm.nih.gov/pubmed/27623007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162931
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