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Functional redundancy of transcription factors explains why most binding targets of a transcription factor are not affected when the transcription factor is knocked out
BACKGROUND: Biologists are puzzled by the extremely low percentage (3%) of the binding targets of a yeast transcription factor (TF) affected when the TF is knocked out, a phenomenon observed by comparing the TF binding dataset and TF knockout effect dataset. RESULTS: This study gives a plausible bio...
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| Publicado no: | BMC Syst Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4674858/ https://ncbi.nlm.nih.gov/pubmed/26678747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-9-S6-S2 |
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