Conditional knock out of transcription factor CTCF in excitatory neurons induces cognitive deficiency

CCCTC-binding factor (CTCF) is a transcription factor that is involved in organizing chromatin structure. A reduction of CTCF expression is known to develop distinct clinical features. Furthermore, conditional knock out (cKO) study revealed reactive gliosis of astrocytes and microglia followed by ag...

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Bibliografiske detaljer
Udgivet i:Mol Brain
Main Authors: Choi, Dong Il, Kim, Myeongwon, Kim, Somi, Yu, Nam-Kyung, Kwak, Chuljung, Seo, Hyunhyo, Lee, Kyungmin, Kaang, Bong-Kiun
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Micro Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7784033/
https://ncbi.nlm.nih.gov/pubmed/33402211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-020-00716-z
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