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Elevated contextual fear memory by SIRT6 depletion in excitatory neurons of mouse forebrain

A class of NAD-dependent protein deacetylases, the Sirtuin (SIRT) family of proteins is involved in aging, cell survival, and neurodegeneration. Recently, SIRT proteins, including SIRT6, have been reported to be important in learning and memory. However, the role of SIRT6 in excitatory brain neurons...

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Détails bibliographiques
Publié dans:Mol Brain
Auteurs principaux: Kim, Hyopil, Kim, Hyun-Seok, Kaang, Bong-Kiun
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6127998/
https://ncbi.nlm.nih.gov/pubmed/30189861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-018-0391-6
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