Excitatory neuron–specific SHP2-ERK signaling network regulates synaptic plasticity and memory

Mutations in RAS signaling pathway components cause diverse neurodevelopmental disorders, collectively called RASopathies. Previous studies have suggested that dysregulation in RAS–extracellular signal–regulated kinase (ERK) activation is restricted to distinct cell types in different RASopathies. S...

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Vydáno v:Sci Signal
Hlavní autoři: Ryu, Hyun-Hee, Kim, TaeHyun, Kim, Jung-Woong, Kang, Minkyung, Park, Pojeong, Kim, Yong Gyu, Kim, Hyopil, Ha, Jiyeon, Choi, Ja Eun, Lee, Jisu, Lim, Chae-Seok, Kim, Chul-Hong, Kim, Sang Jeong, Silva, Alcino J., Kaang, Bong-Kiun, Lee, Yong-Seok
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800025/
https://ncbi.nlm.nih.gov/pubmed/30837304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aau5755
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