Dexamethasone downregulates expression of carbonic anhydrase IX via HIF-1α and NF-κB-dependent mechanisms

Dexamethasone is a synthetic glucocorticoid frequently used to suppress side-effects of anticancer chemotherapy. In the present study, we showed that dexamethasone treatment leads to concentration-dependent downregulation of cancer-associated marker, carbonic anhydrase IX (CA IX), at the level of pr...

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Detalhes bibliográficos
Publicado no:Int J Oncol
Main Authors: Simko, Veronika, Takacova, Martina, Debreova, Michaela, Laposova, Katarina, Ondriskova-Panisova, Elena, Pastorekova, Silvia, Csaderova, Lucia, Pastorek, Jaromir
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021256/
https://ncbi.nlm.nih.gov/pubmed/27431580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2016.3621
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