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MAF1 suppresses AKT‐mTOR signaling and liver cancer through activation of PTEN transcription
The phosphatidylinositol 3‐kinase/phosphatidylinositol 3,4,5‐trisphosphate 3‐phosphatase/protein kinase B/mammalian target of rapamycin (PI3K‐PTEN‐AKT‐mTOR) pathway is a central controller of cell growth and a key driver for human cancer. MAF1 is an mTOR downstream effector and transcriptional repre...
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Publicat a: | Hepatology |
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Autors principals: | , , , , , , , , , |
Format: | Artigo |
Idioma: | Inglês |
Publicat: |
John Wiley and Sons Inc.
2016
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5021206/ https://ncbi.nlm.nih.gov/pubmed/26910647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28507 |
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