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mTOR binds to the promoters of RNA polymerase I- and III-transcribed genes

Target of rapamycin (TOR) is a conserved regulator of gene expression from yeast to humans. In budding yeast, TOR is associated with ribosomal DNA (rDNA) promoter, which is critical for ribosome biogenesis and transfer RNA (tRNA) synthesis. Whether mTOR behaves similarly in mammalian cells is unknow...

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Detalhes bibliográficos
Main Authors: Tsang, Chi Kwan, Liu, Hui, Zheng, X.F. Steven
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023410/
https://ncbi.nlm.nih.gov/pubmed/20038818
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