Visualization of single endogenous polysomes reveals the dynamics of translation in live human cells

Translation is an essential step in gene expression. In this study, we used an improved SunTag system to label nascent proteins and image translation of single messenger ribonucleoproteins (mRNPs) in human cells. Using a dedicated reporter RNA, we observe that translation of single mRNPs stochastica...

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Bibliografiske detaljer
Udgivet i:J Cell Biol
Main Authors: Pichon, Xavier, Bastide, Amandine, Safieddine, Adham, Chouaib, Racha, Samacoits, Aubin, Basyuk, Eugenia, Peter, Marion, Mueller, Florian, Bertrand, Edouard
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2016
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Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021097/
https://ncbi.nlm.nih.gov/pubmed/27597760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201605024
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