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Antitumor effect of novel anti‐podoplanin antibody NZ‐12 against malignant pleural mesothelioma in an orthotopic xenograft model

Podoplanin (aggrus) is highly expressed in several types of cancers, including malignant pleural mesothelioma (MPM). Previously, we developed a rat anti‐human podoplanin mAb, NZ‐1, and a rat–human chimeric anti‐human podoplanin antibody, NZ‐8, derived from NZ‐1, which induced antibody‐dependent cell...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Abe, Shinji, Kaneko, Mika Kato, Tsuchihashi, Yuki, Izumi, Toshihiro, Ogasawara, Satoshi, Okada, Naoto, Sato, Chiemi, Tobiume, Makoto, Otsuka, Kenji, Miyamoto, Licht, Tsuchiya, Koichiro, Kawazoe, Kazuyoshi, Kato, Yukinari, Nishioka, Yasuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021042/
https://ncbi.nlm.nih.gov/pubmed/27294401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12985
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