Nontoxic concentration of DNA‐PK inhibitor NU7441 radio‐sensitizes lung tumor cells with little effect on double strand break repair

High‐linear energy transfer (LET) heavy ions have been increasingly employed as a useful alternative to conventional photon radiotherapy. As recent studies suggested that high LET radiation mainly affects the nonhomologous end‐joining (NHEJ) pathway of DNA double strand break (DSB) repair, we furthe...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancer Sci
Prif Awduron: Sunada, Shigeaki, Kanai, Hideki, Lee, Younghyun, Yasuda, Takeshi, Hirakawa, Hirokazu, Liu, Cuihua, Fujimori, Akira, Uesaka, Mitsuru, Okayasu, Ryuichi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2016
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021029/
https://ncbi.nlm.nih.gov/pubmed/27341700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12998
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