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Histone deacetylase 3 (HDAC 3) as emerging drug target in NF-κB-mediated inflammation
Activation of inflammatory gene expression is regulated, among other factors, by post-translational modifications of histone proteins. The most investigated type of histone modifications are lysine acetylations. Histone deacetylases (HDACs) remove acetylations from lysines, thereby influencing (infl...
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Veröffentlicht in: | Curr Opin Chem Biol |
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Hauptverfasser: | , , |
Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
2016
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5019345/ https://ncbi.nlm.nih.gov/pubmed/27371876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2016.06.019 |
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