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Histone deacetylase 3 (HDAC 3) as emerging drug target in NF-κB-mediated inflammation

Activation of inflammatory gene expression is regulated, among other factors, by post-translational modifications of histone proteins. The most investigated type of histone modifications are lysine acetylations. Histone deacetylases (HDACs) remove acetylations from lysines, thereby influencing (infl...

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Bibliographische Detailangaben
Veröffentlicht in:Curr Opin Chem Biol
Hauptverfasser: Leus, Niek G.J., Zwinderman, Martijn R.H., Dekker, Frank J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5019345/
https://ncbi.nlm.nih.gov/pubmed/27371876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2016.06.019
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