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The Process and Strategy for Developing Selective Histone Deacetylase 3 Inhibitors

Histone deacetylases (HDACs) are epigenetic drug targets that have gained major scientific attention. Inhibition of these important regulatory enzymes is used to treat cancer, and has the potential to treat a host of other diseases. However, currently marketed HDAC inhibitors lack selectivity for th...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Cao, Fangyuan, Zwinderman, Martijn R. H., Dekker, Frank J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6017514/
https://ncbi.nlm.nih.gov/pubmed/29498635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23030551
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