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Screening of selective histone deacetylase inhibitors by proteochemometric modeling
BACKGROUND: Histone deacetylase (HDAC) is a novel target for the treatment of cancer and it can be classified into three classes, i.e., classes I, II, and IV. The inhibitors selectively targeting individual HDAC have been proved to be the better candidate antitumor drugs. To screen selective HDAC in...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3542186/ https://ncbi.nlm.nih.gov/pubmed/22913517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-212 |
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