High affinity and covalent-binding microtubule stabilizing agents show activity in chemotherapy-resistant acute myeloid leukemia cells

Treatment failure in acute myeloid leukemia (AML) is frequently due to the persistence of a cell population resistant to chemotherapy through different mechanisms, in which drug efflux via ATP-binding cassette (ABC) proteins, specifically P-glycoprotein, is one of the most recognized. However, disap...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cancer Lett
Main Authors: Pera, Benet, Calvo-Vidal, M. Nieves, Ambati, Srikanth, Jordi, Michel, Kahn, Alissa, Díaz, J. Fernando, Fang, Weishuo, Altmann, Karl-Heinz, Cerchietti, Leandro, Moore, Malcolm A.S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5019175/
https://ncbi.nlm.nih.gov/pubmed/26277539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2015.07.038
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados