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Parthenolide destabilizes microtubules by covalently modifying tubulin
Detyrosination of the α-tubulin C-terminal tail is a post-translational modification (PTM) of microtubules that is key for many biological processes [1]. Although detyrosination is the oldest known microtubule PTM [2–7], the carboxypeptidase responsible for this modification, VASH1/2-SVBP, was ident...
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| 出版年: | Curr Biol |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7931505/ https://ncbi.nlm.nih.gov/pubmed/33482110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2020.11.055 |
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