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The Added Value of Assessing Ligand–Receptor Binding Kinetics in Drug Discovery

[Image: see text] In the past decade drug research community has started to appreciate the indispensable role of ligand–receptor binding kinetics (BK) in drug discovery. Next to the classical equilibrium-based drug evaluation process with affinity and potency values as outcomes, kinetic investigatio...

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Veröffentlicht in:ACS Med Chem Lett
Hauptverfasser: Guo, Dong, Heitman, Laura H., IJzerman, Adriaan P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2016
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5018870/
https://ncbi.nlm.nih.gov/pubmed/27660682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.6b00273
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