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The Added Value of Assessing Ligand–Receptor Binding Kinetics in Drug Discovery
[Image: see text] In the past decade drug research community has started to appreciate the indispensable role of ligand–receptor binding kinetics (BK) in drug discovery. Next to the classical equilibrium-based drug evaluation process with affinity and potency values as outcomes, kinetic investigatio...
Gespeichert in:
Veröffentlicht in: | ACS Med Chem Lett |
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Hauptverfasser: | , , |
Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
American Chemical
Society
2016
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5018870/ https://ncbi.nlm.nih.gov/pubmed/27660682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.6b00273 |
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