Sustained elevation of NF-κB activity sensitizes offspring of maternal inflammation to hypertension via impairing PGC-1α recovery

Growing evidence has demonstrated that maternal detrimental factors, including inflammation, contribute to the development of hypertension in the offspring. The current study found that offspring subjected to prenatal exposure of inflammation by lipopolysaccharide (LPS) challenge during the second s...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Deng, Yafei, Zhang, Qi, Luo, Hongqin, Chen, Xianhua, Han, Qi, Wang, Fangjie, Huang, Pei, Lai, Wenjing, Guan, Xiao, Pan, Xiaodong, Ji, Yan, Guo, Wei, Che, Ling, Tang, Yuan, Gu, Liangqi, Yu, Jianhua, Namaka, Michael, Deng, Youcai, Li, Xiaohui
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5018852/
https://ncbi.nlm.nih.gov/pubmed/27616627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32642
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