Maternal inflammation activated ROS-p38 MAPK predisposes offspring to heart damages caused by isoproterenol via augmenting ROS generation

Maternal inflammation contributes to the increased incidence of adult cardiovascular disease. The current study investigated the susceptibility of cardiac damage responding to isoproterenol (ISO) in adult offspring that underwent maternal inflammation (modeled by pregnant Sprague-Dawley rats with li...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Qi, Deng, Yafei, Lai, Wenjing, Guan, Xiao, Sun, Xiongshan, Han, Qi, Wang, Fangjie, Pan, Xiaodong, Ji, Yan, Luo, Hongqin, Huang, Pei, Tang, Yuan, Gu, Liangqi, Dan, Guorong, Yu, Jianhua, Namaka, Michael, Zhang, Jianxiang, Deng, Youcai, Li, Xiaohui
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957145/
https://ncbi.nlm.nih.gov/pubmed/27443826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30146
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