Maternal inflammation activated ROS-p38 MAPK predisposes offspring to heart damages caused by isoproterenol via augmenting ROS generation

Maternal inflammation contributes to the increased incidence of adult cardiovascular disease. The current study investigated the susceptibility of cardiac damage responding to isoproterenol (ISO) in adult offspring that underwent maternal inflammation (modeled by pregnant Sprague-Dawley rats with li...

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Pubblicato in:Sci Rep
Autori principali: Zhang, Qi, Deng, Yafei, Lai, Wenjing, Guan, Xiao, Sun, Xiongshan, Han, Qi, Wang, Fangjie, Pan, Xiaodong, Ji, Yan, Luo, Hongqin, Huang, Pei, Tang, Yuan, Gu, Liangqi, Dan, Guorong, Yu, Jianhua, Namaka, Michael, Zhang, Jianxiang, Deng, Youcai, Li, Xiaohui
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957145/
https://ncbi.nlm.nih.gov/pubmed/27443826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30146
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