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Ursolic acid sensitized colon cancer cells to chemotherapy under hypoxia by inhibiting MDR1 through HIF-1α
Objective: To explore the efficacy of ursolic acid in sensitizing colon cancer cells to chemotherapy under hypoxia and its underlying mechanisms. Methods: Three colon cancer cell lines (RKO, LoVo, and SW480) were used as in vitro models. 5-Fluorouracil (5-FU) and oxaliplatin were used as chemotherap...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | J Zhejiang Univ Sci B |
|---|---|
| Prif Awduron: | , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Zhejiang University Press
2016
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5018614/ https://ncbi.nlm.nih.gov/pubmed/27604859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1631/jzus.B1600266 |
| Tagiau: |
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