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Ursolic acid inhibits proliferation and induces apoptosis of HT-29 colon cancer cells by inhibiting the EGFR/MAPK pathway

Objective: To investigate the effects of ursolic acid on the proliferation and apoptosis of human HT-29 colon cancer cells. Methods: 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) and flow cytometry assays were performed to evaluate the effects of ursolic acid on the growth and a...

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Detalhes bibliográficos
Main Authors: Shan, Jian-zhen, Xuan, Yan-yan, Zheng, Shu, Dong, Qi, Zhang, Su-zhan
Formato: Artigo
Idioma:Inglês
Publicado em: Zhejiang University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738836/
https://ncbi.nlm.nih.gov/pubmed/19735099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1631/jzus.B0920149
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