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Sunitinib mesylate inhibits proliferation of human colonic stromal fibroblasts in vitro and in vivo

Objective: Cancer stromal fibroblasts are important members of the cancer microenvironment. In this study, we determined the effect of sunitinib, a small molecule tyrosine kinase inhibitor, on the primary human colonic fibroblasts. Methods: Cell cycle analysis and cell proliferation assays were perf...

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Detalhes bibliográficos
Main Authors: Wang, Zhan-huai, Li, Qiong, Ruan, Shu-qin, Xiao, Qian, Liu, Yue, Hu, Ye-ting, Hu, Li-feng, Chen, Hai-yan, Zheng, Shu, Zhang, Su-zhan, Ding, Ke-feng
Formato: Artigo
Idioma:Inglês
Publicado em: Zhejiang University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4129090/
https://ncbi.nlm.nih.gov/pubmed/25091988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1631/jzus.B1300306
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