Transgenic GDNF Positively Influences Proliferation, Differentiation, Maturation and Survival of Motor Neurons Produced from Mouse Embryonic Stem Cells

Embryonic stem cells (ESC) are pluripotent and thus can differentiate into every cell type present in the body. Directed differentiation into motor neurons (MNs) has been described for pluripotent cells. Although neurotrophic factors promote neuronal survival, their role in neuronal commitment is el...

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Detalles Bibliográficos
Publicado en:Front Cell Neurosci
Autores principales: Cortés, Daniel, Robledo-Arratia, Yolanda, Hernández-Martínez, Ricardo, Escobedo-Ávila, Itzel, Bargas, José, Velasco, Iván
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2016
Materias:
Neuroscience
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5018488/
https://ncbi.nlm.nih.gov/pubmed/27672361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2016.00217
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