Transgenic GDNF Positively Influences Proliferation, Differentiation, Maturation and Survival of Motor Neurons Produced from Mouse Embryonic Stem Cells

Embryonic stem cells (ESC) are pluripotent and thus can differentiate into every cell type present in the body. Directed differentiation into motor neurons (MNs) has been described for pluripotent cells. Although neurotrophic factors promote neuronal survival, their role in neuronal commitment is el...

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Bibliografski detalji
Izdano u:Front Cell Neurosci
Glavni autori: Cortés, Daniel, Robledo-Arratia, Yolanda, Hernández-Martínez, Ricardo, Escobedo-Ávila, Itzel, Bargas, José, Velasco, Iván
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2016
Teme:
Neuroscience
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5018488/
https://ncbi.nlm.nih.gov/pubmed/27672361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2016.00217
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