Transgenic GDNF Positively Influences Proliferation, Differentiation, Maturation and Survival of Motor Neurons Produced from Mouse Embryonic Stem Cells

Embryonic stem cells (ESC) are pluripotent and thus can differentiate into every cell type present in the body. Directed differentiation into motor neurons (MNs) has been described for pluripotent cells. Although neurotrophic factors promote neuronal survival, their role in neuronal commitment is el...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Cortés, Daniel, Robledo-Arratia, Yolanda, Hernández-Martínez, Ricardo, Escobedo-Ávila, Itzel, Bargas, José, Velasco, Iván
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5018488/
https://ncbi.nlm.nih.gov/pubmed/27672361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2016.00217
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