Pax6 associates with H3K4-specific histone methyltransferases Mll1, Mll2, and Set1a and regulates H3K4 methylation at promoters and enhancers

BACKGROUND: Pax6 is a key regulator of the entire cascade of ocular lens formation through specific binding to promoters and enhancers of batteries of target genes. The promoters and enhancers communicate with each other through DNA looping mediated by multiple protein–DNA and protein–protein intera...

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Detalhes bibliográficos
Publicado no:Epigenetics Chromatin
Main Authors: Sun, Jian, Zhao, Yilin, McGreal, Rebecca, Cohen-Tayar, Yamit, Rockowitz, Shira, Wilczek, Carola, Ashery-Padan, Ruth, Shechter, David, Zheng, Deyou, Cvekl, Ales
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5018195/
https://ncbi.nlm.nih.gov/pubmed/27617035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-016-0087-z
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