Identification of in vivo DNA-binding mechanisms of Pax6 and reconstruction of Pax6-dependent gene regulatory networks during forebrain and lens development

The transcription factor Pax6 is comprised of the paired domain (PD) and homeodomain (HD). In the developing forebrain, Pax6 is expressed in ventricular zone precursor cells and in specific subpopulations of neurons; absence of Pax6 results in disrupted cell proliferation and cell fate specification...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Sun, Jian, Rockowitz, Shira, Xie, Qing, Ashery-Padan, Ruth, Zheng, Deyou, Cvekl, Ales
Format: Artigo
Language:Inglês
Published: Oxford University Press 2015
Subjects:
Gene regulation, Chromatin and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538810/
https://ncbi.nlm.nih.gov/pubmed/26138486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv589
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