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Identification of in vivo DNA-binding mechanisms of Pax6 and reconstruction of Pax6-dependent gene regulatory networks during forebrain and lens development

The transcription factor Pax6 is comprised of the paired domain (PD) and homeodomain (HD). In the developing forebrain, Pax6 is expressed in ventricular zone precursor cells and in specific subpopulations of neurons; absence of Pax6 results in disrupted cell proliferation and cell fate specification...

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Библиографические подробности
Опубликовано в: :Nucleic Acids Res
Главные авторы: Sun, Jian, Rockowitz, Shira, Xie, Qing, Ashery-Padan, Ruth, Zheng, Deyou, Cvekl, Ales
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538810/
https://ncbi.nlm.nih.gov/pubmed/26138486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv589
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