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ASCT2 (SLC1A5) is an EGFR-associated protein that can be co-targeted by cetuximab to sensitize cancer cells to ROS-induced apoptosis
Therapeutic targeting of ASCT2, a glutamine transporter that plays a major role in glutamine uptake in cancer cells, is challenging because ASCT2 also has a biological role in normal tissue. In this study, we report our novel finding that ASCT2 is physically associated in a molecular complex with ep...
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| Publicado no: | Cancer Lett |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5017913/ https://ncbi.nlm.nih.gov/pubmed/27450723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2016.07.020 |
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