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Roles of autophagy in cetuximab-mediated cancer therapy against EGFR
Cetuximab is an epidermal growth factor receptor (EGFR)-blocking antibody that is approved to treat several types of solid cancers in patients. We recently showed that cetuximab can induce autophagy in cancer cells by both inhibiting the class I phosphatidylinositol 3-kinase (PtdIns3K)/Akt/mammalian...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3039478/ https://ncbi.nlm.nih.gov/pubmed/20864811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.6.8.13366 |
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