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AP1G1 is involved in cetuximab-mediated downregulation of ASCT2-EGFR complex and sensitization of human head and neck squamous cell carcinoma cells to ROS-induced apoptosis

In this study, we expanded our recent work showing that ASCT2, a Na+-dependent neutral amino acid transporter that plays a major role in glutamine uptake in cancer cells, is physically associated with EGFR in human head and neck squamous cell carcinoma cells and in several other types of cancer cell...

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Detalhes bibliográficos
Publicado no:Cancer Lett
Main Authors: Tao, Xiaoan, Lu, Yang, Qiu, Songbo, Wang, Yi, Qin, Jun, Fan, Zhen
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5628150/
https://ncbi.nlm.nih.gov/pubmed/28823958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2017.08.012
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