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Resolving the contributions of two cooperative mechanisms to the DNA Binding of AGT

The O(6)‐alkylguanine DNA alkyltransferase (AGT) is a DNA repair enzyme that binds DNA with moderate cooperativity. This cooperativity is important for its search for alkylated bases. A structural model of the cooperative complex of AGT with DNA predicts short‐range interactions between nearest prot...

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Detalhes bibliográficos
Publicado no:Biopolymers
Main Authors: Melikishvili, Manana, Fried, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016775/
https://ncbi.nlm.nih.gov/pubmed/26017689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.22684
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