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Alternative splicing and nonsense-mediated mRNA decay enforce neural specific gene expression
Alternative pre-mRNA splicing is a fundamental regulatory process for most mammalian multi-exon genes to increase proteome diversity. Nonsense-mediated mRNA decay (NMD) is a conserved mRNA surveillance mechanism to mitigate deleterious effects caused by gene mutations or transcriptional errors. Coup...
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Publicado no: | Int J Dev Neurosci |
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Autor principal: | |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5016260/ https://ncbi.nlm.nih.gov/pubmed/26968265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijdevneu.2016.03.003 |
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