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Alternative splicing and nonsense-mediated mRNA decay enforce neural specific gene expression

Alternative pre-mRNA splicing is a fundamental regulatory process for most mammalian multi-exon genes to increase proteome diversity. Nonsense-mediated mRNA decay (NMD) is a conserved mRNA surveillance mechanism to mitigate deleterious effects caused by gene mutations or transcriptional errors. Coup...

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Detalhes bibliográficos
Publicado no:Int J Dev Neurosci
Autor principal: Zheng, Sika
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016260/
https://ncbi.nlm.nih.gov/pubmed/26968265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijdevneu.2016.03.003
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