NGF-TrkA signaling by sensory nerves coordinates the vascularization and ossification of developing endochondral bone

Developing tissues dictate the amount and type of innervation they require by secreting neurotrophins, which promote neuronal survival by activating distinct tyrosine kinase receptors. Here, we show that NGF-TrkA signaling directs innervation of the developing mouse femur to promote vascularization...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Cell Rep
Autori principali: Tomlinson, Ryan E., Li, Zhi, Zhang, Qian, Goh, Brian C., Li, Zhu, Thorek, Daniel L. J., Rajbhandari, Labchan, Brushart, Thomas M., Minichiello, Liliana, Zhou, Fengquan, Venkatesan, Arun, Clemens, Thomas L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014649/
https://ncbi.nlm.nih.gov/pubmed/27568565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.08.002
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi