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NGF-TrkA signaling in sensory nerves is required for skeletal adaptation to mechanical loads in mice
Sensory nerves emanating from the dorsal root extensively innervate the surfaces of mammalian bone, a privileged location for the regulation of biomechanical signaling. Here, we show that NGF-TrkA signaling in skeletal sensory nerves is an early response to mechanical loading of bone and is required...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5422802/ https://ncbi.nlm.nih.gov/pubmed/28416686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1701054114 |
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