NGF-TrkA signaling by sensory nerves coordinates the vascularization and ossification of developing endochondral bone

Developing tissues dictate the amount and type of innervation they require by secreting neurotrophins, which promote neuronal survival by activating distinct tyrosine kinase receptors. Here, we show that NGF-TrkA signaling directs innervation of the developing mouse femur to promote vascularization...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Tomlinson, Ryan E., Li, Zhi, Zhang, Qian, Goh, Brian C., Li, Zhu, Thorek, Daniel L. J., Rajbhandari, Labchan, Brushart, Thomas M., Minichiello, Liliana, Zhou, Fengquan, Venkatesan, Arun, Clemens, Thomas L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014649/
https://ncbi.nlm.nih.gov/pubmed/27568565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.08.002
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