NGF-TrkA signaling by sensory nerves coordinates the vascularization and ossification of developing endochondral bone

Developing tissues dictate the amount and type of innervation they require by secreting neurotrophins, which promote neuronal survival by activating distinct tyrosine kinase receptors. Here, we show that NGF-TrkA signaling directs innervation of the developing mouse femur to promote vascularization...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Rep
Prif Awduron: Tomlinson, Ryan E., Li, Zhi, Zhang, Qian, Goh, Brian C., Li, Zhu, Thorek, Daniel L. J., Rajbhandari, Labchan, Brushart, Thomas M., Minichiello, Liliana, Zhou, Fengquan, Venkatesan, Arun, Clemens, Thomas L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014649/
https://ncbi.nlm.nih.gov/pubmed/27568565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.08.002
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